Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway

Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway

<p dir="ltr">Multiple myeloma (MM) is a hematologic malignancy associated with malignant plasma cell proliferation in the bone marrow. Despite the available treatments, drug resistance and adverse side effects pose significant challenges, underscoring the need for alternative therape...

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Bibliographic Details
Main Author: Shilpa Kuttikrishnan (3520079) (author)
Other Authors: Fareed Ahmad (134672) (author), Jericha M. Mateo (17563293) (author), Kirti S. Prabhu (4246144) (author), Tamam El‐Elimat (17714580) (author), Nicholas H. Oberlies (326437) (author), Cedric J. Pearce (1364220) (author), Ammira S. Alshabeeb Akil (15430143) (author), Ajaz A. Bhat (12984701) (author), Feras Q. Alali (2691907) (author), Shahab Uddin (154400) (author)
Published: 2023
Subjects:
Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Oncology and carcinogenesis
Pharmacology and pharmaceutical sciences
AKT
caspases
drug synergy
multiple myeloma
neosetophomone B
SKP2
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