The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants

The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants

<p dir="ltr">The inclusion of familial myeloid malignancies as a separate disease entity in the revised WHO classification has renewed efforts to improve the recognition and management of this group of at risk individuals. Here we report a cohort of 86 acute myeloid leukemia (AML) an...

Full description

Saved in:
Bibliographic Details
Main Author: Ana Rio-Machin (19686124) (author)
Other Authors: Tom Vulliamy (110425) (author), Nele Hug (16228043) (author), Amanda Walne (205621) (author), Kiran Tawana (19686127) (author), Shirleny Cardoso (19686130) (author), Alicia Ellison (19686133) (author), Nikolas Pontikos (4611358) (author), Jun Wang (5906) (author), Hemanth Tummala (209932) (author), Ahad Fahad H. Al Seraihi (19686136) (author), Jenna Alnajar (13227864) (author), Findlay Bewicke-Copley (485083) (author), Hannah Armes (19686139) (author), Michael Barnett (317282) (author), Adrian Bloor (3520115) (author), Csaba Bödör (483098) (author), David Bowen (89572) (author), Pierre Fenaux (751250) (author), Andrew Green (2960511) (author), Andrew Hallahan (11206439) (author), Henrik Hjorth-Hansen (3704839) (author), Upal Hossain (205601) (author), Sally Killick (89570) (author), Sarah Lawson (6194801) (author), Mark Layton (11457303) (author), Alison M. Male (19686142) (author), Judith Marsh (205617) (author), Priyanka Mehta (3213543) (author), Rogier Mous (15036779) (author), Josep F. Nomdedéu (19686145) (author), Carolyn Owen (19686148) (author), Jiri Pavlu (6330410) (author), Elspeth M. Payne (11424145) (author), Rachel E. Protheroe (19686151) (author), Claude Preudhomme (356069) (author), Nuria Pujol-Moix (805671) (author), Aline Renneville (114625) (author), Nigel Russell (3177729) (author), Anand Saggar (16045313) (author), Gabriela Sciuccati (19686154) (author), David Taussig (7944140) (author), Cynthia L. Toze (19686157) (author), Anne Uyttebroeck (160862) (author), Peter Vandenberghe (160870) (author), Brigitte Schlegelberger (136771) (author), Tim Ripperger (5612297) (author), Doris Steinemann (214253) (author), John Wu (681395) (author), Joanne Mason (3520556) (author), Paula Page (7389467) (author), Susanna Akiki (19684909) (author), Kim Reay (19686160) (author), Jamie D. Cavenagh (15010380) (author), Vincent Plagnol (50600) (author), Javier F. Caceres (5651266) (author), Jude Fitzgibbon (483100) (author), Inderjeet Dokal (205627) (author)
Published: 2020
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Clinical sciences
Familial Myeloid Malignancies
Acute Myeloid Leukemia (AML)
Germline Variants
Genetic Loci
Whole Exome Sequencing
Hematological Syndromes
Inherited Bone Marrow Failure
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items