Curcumin induces apoptosis via downregulation of SKP2 and induction of GADD45A/CDKN1A expression through generation of ROS in cutaneous T-cell lymphoma cells

Curcumin induces apoptosis via downregulation of SKP2 and induction of GADD45A/CDKN1A expression through generation of ROS in cutaneous T-cell lymphoma cells

<p dir="ltr"><u>Curcumin</u>, a plant derived <u>natural product</u> isolated from <u>Curcuma</u> longa. The aim of this study is to investigate the anti-proliferative effects and the underlying mechanisms of curcumin in Cutaneous <u>T cell&l...

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Bibliographic Details
Main Author: Shilpa Kuttikrishnan (3520079) (author)
Other Authors: Muhammad Suleman (3829027) (author), Fareed Ahmad (134672) (author), Zahwa Mariyam (22504034) (author), Ummu Habeeba (22504037) (author), Kirti S. Prabhu (4246144) (author), Joerg Buddenkotte (6293584) (author), Martin Steinhoff (5340194) (author), Shahab Uddin (154400) (author)
Published: 2025
Subjects:
Biomedical and clinical sciences
Clinical sciences
Oncology and carcinogenesis
Pharmacology and pharmaceutical sciences
Curcumin
CTCL
SKP2
GADD45
Apoptosis
Caspases
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