Modulation of Human Valve Interstitial Cell Phenotype and Function Using a Fibroblast Growth Factor 2 Formulation

Modulation of Human Valve Interstitial Cell Phenotype and Function Using a Fibroblast Growth Factor 2 Formulation

<p dir="ltr">Valve interstitial cells (VICs) are fibroblastic in nature however in culture it is widely accepted that they differentiate into a myofibroblastic phenotype. This study assessed a fibroblast culture media formulation for its ability to maintain the phenotype and function...

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Bibliographic Details
Main Author: Najma Latif (250130) (author)
Other Authors: Alfred Quillon (749637) (author), Padmini Sarathchandra (124189) (author), Ann McCormack (749638) (author), Alec Lozanoski (749639) (author), Magdi H. Yacoub (9525114) (author), Adrian H. Chester (9525117) (author)
Published: 2015
Subjects:
Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Cardiovascular medicine and haematology
Engineering
Biomedical engineering
Fibroblasts
Fibroblast growth factor
Focal adhesions
Cell differentiation
Collagens
Aspect ratio
Extracellular matrix proteins
Insulin
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