Investigation of the Effect of PD-L1 Blockade on Triple Negative Breast Cancer Cells Using Fourier Transform Infrared Spectroscopy

Investigation of the Effect of PD-L1 Blockade on Triple Negative Breast Cancer Cells Using Fourier Transform Infrared Spectroscopy

<div><p>Interactions between programmed death-1 (PD-1) with its ligand PD-L1 on tumor cells can antagonize T cell responses. Inhibiting these interactions using immune checkpoint inhibitors has shown promise in cancer immunotherapy. MDA-MB-231 is a triple negative breast cancer cell line...

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Bibliographic Details
Main Author: Mohamed H. M. Ali (5768066) (author)
Other Authors: Salman M Toor (9279953) (author), Fazle Rakib (5768069) (author), Raghvendra Mall (581171) (author), Ehsan Ullah (2698921) (author), Kamal Mroue (14152491) (author), Prasanna R. Kolatkar (124118) (author), Khalid Al-Saad (5768084) (author), Eyad Elkord (5396390) (author)
Published: 2019
Subjects:
Biomedical and clinical sciences
Oncology and carcinogenesis
breast cancer
tumor cells
spectroscopy
FTIR
biochemical alterations
chemometric analysis
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