Identification of a potential DNA methyltransferase (DNMT) inhibitor

Identification of a potential DNA methyltransferase (DNMT) inhibitor

<p dir="ltr">DNA methyltransferases (DNMTs) play an important role in the epigenetic regulation of gene expression through the methylation of DNA. Since hypermethylation and consequent suppression of tumor suppressor genes are associated with cancer development and progression, DNA h...

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Bibliographic Details
Main Author: Zainab Jan (17306614) (author)
Other Authors: Wesam S. Ahmed (10170053) (author), Kabir H. Biswas (5705864) (author), Puthen Veettil Jithesh (12040358) (author)
Published: 2023
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Oncology and carcinogenesis
Pharmacology and pharmaceutical sciences
DNA methyltransferases
DNMT inhibitors
drug discovery
DNA hypomethylating agents
virtual screening
cancer therapy
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