Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus

Ribosomal DNA Copy Number Variation is Coupled with DNA Methylation Changes at the 45S rDNA Locus

<p dir="ltr">The human ribosomal DNA (rDNA) copy number (CN) has been challenging to analyse, and its sequence has been excluded from reference genomes due to its highly repetitive nature. The 45S rDNA locus encodes essential components of the cell, nevertheless rDNA displays high in...

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Bibliographic Details
Main Author: Aleem Razzaq (14779189) (author)
Other Authors: Yosra Bejaoui (8552574) (author), Tanvir Alam (638619) (author), Mohamad Saad (214545) (author), Nady El Hajj (686554) (author)
Published: 2023
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Clinical sciences
Engineering
Biomedical engineering
Ribosomal DNA
Copy number
DNA methylation
Autism spectrum disorder
Schizophrenia
Dosage compensation
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