SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
<p dir="ltr">The present study describes the synthesis of a series of 22 chalcone analogs. These compounds were evaluated as potential human MAO-A and MAO-B inhibitors. The compounds showed varied selectivity against the two isoforms. The IC<sub>50</sub> values were found...
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| Main Author: | Raed Shalaby (3756112) (author) |
|---|---|
| Other Authors: | Jacobus P. Petzer (1395751) (author), Anél Petzer (6517940) (author), Usman M. Ashraf (6517943) (author), Ealla Atari (6517946) (author), Fawaz Alasmari (6517949) (author), Sivarajan Kumarasamy (6517952) (author), Youssef Sari (308864) (author), Ashraf Khalil (4591618) (author) |
| Published: |
2019
|
| Subjects: | |
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