Biallelic TLR4 deficiency in humans

Biallelic TLR4 deficiency in humans

<h3>Background </h3><p dir="ltr">Toll-like receptors (TLRs) mediate functions for host defense and inflammatory responses. TLR4 recognizes LPS, a component of gram-negative bacteria as well as host-derived endogenous ligands such as S100A8 and S100A9 proteins. </p>&...

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Main Author: Melania Capitani (17238355) (author)
Other Authors: Ahmad A. Al-Shaibi (19482409) (author), Sumeet Pandey (7010018) (author), Lisa Gartner (19482412) (author), Henry Taylor (6737321) (author), Satanay Z. Hubrack (19482415) (author), Nourhen Agrebi (14151222) (author), Muneera Jassim Al-Mohannadi (14166138) (author), Saad Al Kaabi (18112780) (author), Thomas Vogl (125044) (author), Johannes Roth (125060) (author), Daniel Kotlarz (6473711) (author), Christoph Klein (157998) (author), Adrian K. Charles (15084250) (author), Vinayan Vijayakumar (19482418) (author), Mohammed Yousuf Karim (8602092) (author), Bruce George (19482421) (author), Simon P. Travis (19482424) (author), Mamoun Elawad (438979) (author), Bernice Lo (3441317) (author), Holm H. Uhlig (8163909) (author)
Published: 2023
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Clinical sciences
Immunology
Inflammatory bowel disease
primary immunodeficiency
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