Targeting Wnt/EZH2/microRNA-708 signaling pathway inhibits neuroendocrine differentiation in prostate cancer

Targeting Wnt/EZH2/microRNA-708 signaling pathway inhibits neuroendocrine differentiation in prostate cancer

<p>Prostate cancer (PC) castration resistance has been linked to the differentiation of PC luminal cells into hormone-refractory neuroendocrine (NE) cells. However, the molecular mechanisms controlling the emergence of lethal NE prostate cancer (NEPC) remain unclear. The present study aimed to...

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Bibliographic Details
Main Author: Jingxuan Shan (14152608) (author)
Other Authors: Mariam A. Al-Muftah (14152611) (author), Moza K. Al-Kowari (14152614) (author), Sirin W. J. Abuaqel (14152617) (author), Khalid Al-Rumaihi (4711095) (author), Issam Al-Bozom (4711098) (author), Pu Li (119107) (author), Lotfi Chouchane (61840) (author)
Published: 2019
Subjects:
Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Oncology and carcinogenesis
Cancer Research
Cell Biology
Cellular and Molecular Neuroscience
Immunology
Prostate Cancer (PC)
Cancer Stem
Cells Tumorigenesis
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