Effects of khat <i>(Catha edulis) </i>chewing on dry mouth and taste function: A comparative cross-sectional study
<h3>Objectives</h3><p dir="ltr">To evaluate oral dryness and the taste sensation threshold (sweet, salt, sour, bitter) among khat chewers.</p><h3>Method</h3><p dir="ltr">This cross-sectional comparative study enrolled 140 healthy individu...
محفوظ في:
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| مؤلفون آخرون: | , , , |
| منشور في: |
2025
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| الموضوعات: | |
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إضافة وسم
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| _version_ | 1864513547327766528 |
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| author | Ola Mohsen Al-Akwa'a (21153305) |
| author2 | Manal Mohammed AL-Hajri (21153308) Asma'a Mansour ALHowshabi (21153311) Sadeq Ali Al-Maweri (10412616) Esam Halboub (6302024) |
| author2_role | author author author author |
| author_facet | Ola Mohsen Al-Akwa'a (21153305) Manal Mohammed AL-Hajri (21153308) Asma'a Mansour ALHowshabi (21153311) Sadeq Ali Al-Maweri (10412616) Esam Halboub (6302024) |
| author_role | author |
| dc.creator.none.fl_str_mv | Ola Mohsen Al-Akwa'a (21153305) Manal Mohammed AL-Hajri (21153308) Asma'a Mansour ALHowshabi (21153311) Sadeq Ali Al-Maweri (10412616) Esam Halboub (6302024) |
| dc.date.none.fl_str_mv | 2025-04-11T09:00:00Z |
| dc.identifier.none.fl_str_mv | 10.1016/j.oooo.2025.03.016 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/journal_contribution/Effects_of_khat_i_Catha_edulis_i_chewing_on_dry_mouth_and_taste_function_A_comparative_cross-sectional_study/28829567 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Biomedical and clinical sciences Dentistry Pharmacology and pharmaceutical sciences Health sciences Public health oral dryness taste impairment khat chewing |
| dc.title.none.fl_str_mv | Effects of khat <i>(Catha edulis) </i>chewing on dry mouth and taste function: A comparative cross-sectional study |
| dc.type.none.fl_str_mv | Text Journal contribution info:eu-repo/semantics/publishedVersion text contribution to journal |
| description | <h3>Objectives</h3><p dir="ltr">To evaluate oral dryness and the taste sensation threshold (sweet, salt, sour, bitter) among khat chewers.</p><h3>Method</h3><p dir="ltr">This cross-sectional comparative study enrolled 140 healthy individuals divided into two groups: khat chewers (KC; n = 73), and non-chewers (NC; n = 67). Oral dryness was assessed using the Clinical Oral Dryness Score (CODS), while taste perception was assessed using the four primary tastes: sweet, salt, sour, bitter, along with the Total Taste Score (TTS), each prepared as seven chemical solutions representing seven concentrations. SPSS V. 26 was used for data analysis.</p><h3>Results</h3><p dir="ltr">Overall, KC revealed significantly higher overall CODS scores compared to NC (4.26±1.39 vs. 2.10±1.15; <i>P</i> < 0.001). The TTS was significantly lower in KC (16.52 ± 3.367) compared to NC (18.87 ± 3.592; <i>P</i> < 0.001), owing to revealing significantly lower mean taste sensation scores for sweet, salty, and bitter tastants, but not for sour taste. Up to 20.5% of KC had hypogeusia compared to only 4.5% of NC (<i>P</i> = 0.005). Multivariate analyses also revealed khat chewing as an independent determinant factor for oral dryness and hypogeusia.</p><h3>Conclusion</h3><p dir="ltr">Chronic khat chewing is associated with mouth dryness and taste impairment, gravely impacting on the patients’ quality of life.</p><h2>Other Information</h2><p dir="ltr">Published in: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.oooo.2025.03.016" target="_blank">https://dx.doi.org/10.1016/j.oooo.2025.03.016</a></p> |
| eu_rights_str_mv | openAccess |
| id | Manara2_9047329d25a1f12a0f04425f8bb06ce7 |
| identifier_str_mv | 10.1016/j.oooo.2025.03.016 |
| network_acronym_str | Manara2 |
| network_name_str | Manara2 |
| oai_identifier_str | oai:figshare.com:article/28829567 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Effects of khat <i>(Catha edulis) </i>chewing on dry mouth and taste function: A comparative cross-sectional studyOla Mohsen Al-Akwa'a (21153305)Manal Mohammed AL-Hajri (21153308)Asma'a Mansour ALHowshabi (21153311)Sadeq Ali Al-Maweri (10412616)Esam Halboub (6302024)Biomedical and clinical sciencesDentistryPharmacology and pharmaceutical sciencesHealth sciencesPublic healthoral drynesstaste impairmentkhat chewing<h3>Objectives</h3><p dir="ltr">To evaluate oral dryness and the taste sensation threshold (sweet, salt, sour, bitter) among khat chewers.</p><h3>Method</h3><p dir="ltr">This cross-sectional comparative study enrolled 140 healthy individuals divided into two groups: khat chewers (KC; n = 73), and non-chewers (NC; n = 67). Oral dryness was assessed using the Clinical Oral Dryness Score (CODS), while taste perception was assessed using the four primary tastes: sweet, salt, sour, bitter, along with the Total Taste Score (TTS), each prepared as seven chemical solutions representing seven concentrations. SPSS V. 26 was used for data analysis.</p><h3>Results</h3><p dir="ltr">Overall, KC revealed significantly higher overall CODS scores compared to NC (4.26±1.39 vs. 2.10±1.15; <i>P</i> < 0.001). The TTS was significantly lower in KC (16.52 ± 3.367) compared to NC (18.87 ± 3.592; <i>P</i> < 0.001), owing to revealing significantly lower mean taste sensation scores for sweet, salty, and bitter tastants, but not for sour taste. Up to 20.5% of KC had hypogeusia compared to only 4.5% of NC (<i>P</i> = 0.005). Multivariate analyses also revealed khat chewing as an independent determinant factor for oral dryness and hypogeusia.</p><h3>Conclusion</h3><p dir="ltr">Chronic khat chewing is associated with mouth dryness and taste impairment, gravely impacting on the patients’ quality of life.</p><h2>Other Information</h2><p dir="ltr">Published in: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.oooo.2025.03.016" target="_blank">https://dx.doi.org/10.1016/j.oooo.2025.03.016</a></p>2025-04-11T09:00:00ZTextJournal contributioninfo:eu-repo/semantics/publishedVersiontextcontribution to journal10.1016/j.oooo.2025.03.016https://figshare.com/articles/journal_contribution/Effects_of_khat_i_Catha_edulis_i_chewing_on_dry_mouth_and_taste_function_A_comparative_cross-sectional_study/28829567CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/288295672025-04-11T09:00:00Z |
| spellingShingle | Effects of khat <i>(Catha edulis) </i>chewing on dry mouth and taste function: A comparative cross-sectional study Ola Mohsen Al-Akwa'a (21153305) Biomedical and clinical sciences Dentistry Pharmacology and pharmaceutical sciences Health sciences Public health oral dryness taste impairment khat chewing |
| status_str | publishedVersion |
| title | Effects of khat <i>(Catha edulis) </i>chewing on dry mouth and taste function: A comparative cross-sectional study |
| title_full | Effects of khat <i>(Catha edulis) </i>chewing on dry mouth and taste function: A comparative cross-sectional study |
| title_fullStr | Effects of khat <i>(Catha edulis) </i>chewing on dry mouth and taste function: A comparative cross-sectional study |
| title_full_unstemmed | Effects of khat <i>(Catha edulis) </i>chewing on dry mouth and taste function: A comparative cross-sectional study |
| title_short | Effects of khat <i>(Catha edulis) </i>chewing on dry mouth and taste function: A comparative cross-sectional study |
| title_sort | Effects of khat <i>(Catha edulis) </i>chewing on dry mouth and taste function: A comparative cross-sectional study |
| topic | Biomedical and clinical sciences Dentistry Pharmacology and pharmaceutical sciences Health sciences Public health oral dryness taste impairment khat chewing |