Flavin Adenine Dinucleotide (FAD) and Pyridoxal 5′-Phosphate (PLP) Bind to Sox9 and Alter the Expression of Key Pancreatic Progenitor Transcription Factors

Flavin Adenine Dinucleotide (FAD) and Pyridoxal 5′-Phosphate (PLP) Bind to Sox9 and Alter the Expression of Key Pancreatic Progenitor Transcription Factors

<div><p>Cofactor flavin adenine dinucleotide (FAD), a compound with flavin moiety and a derivative of riboflavin (vitamin B2), is shown to bind to Sox9 (a key transcription factor in early pancreatic development) and, subsequently, induce a large increase in markers of pancreatic develop...

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Bibliographic Details
Main Author: Zeyaul Islam (5867387) (author)
Other Authors: Noura Aldous (15429873) (author), Sunkyu Choi (2141545) (author), Frank Schmidt (207186) (author), Borbala Mifsud (3907267) (author), Essam M. Abdelalim (5768072) (author), Prasanna R. Kolatkar (124118) (author)
Published: 2022
Subjects:
Chemical sciences
Inorganic chemistry
Organic chemistry
Theoretical and computational chemistry
pancreatic progenitors
Sox9
FAD
PLP
transcription factor
Sox family
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