Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline
<p dir="ltr">In somatic cells/tissues, methylation of ribosomal DNA (rDNA) increases with age and age‐related pathologies, which has a direct impact on the regulation of nucleolar activity and cellular metabolism. Here, we used bisulfite pyrosequencing and show that methylation of th...
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2020
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