Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline
<p dir="ltr">In somatic cells/tissues, methylation of ribosomal DNA (rDNA) increases with age and age‐related pathologies, which has a direct impact on the regulation of nucleolar activity and cellular metabolism. Here, we used bisulfite pyrosequencing and show that methylation of th...
محفوظ في:
| المؤلف الرئيسي: | Ramya Potabattula (4401160) (author) |
|---|---|
| مؤلفون آخرون: | Federica Zacchini (289957) (author), Grazyna Ewa Ptak (18877204) (author), Marcus Dittrich (167737) (author), Tobias Müller (163591) (author), Nady El Hajj (686554) (author), Thomas Hahn (146530) (author), Charis Drummer (18710925) (author), Rüdiger Behr (705041) (author), Andrea Lucas‐Hahn (18877207) (author), Heiner Niemann (196135) (author), Martin Schorsch (686559) (author), Thomas Haaf (342924) (author) |
| منشور في: |
2020
|
| الموضوعات: | |
| الوسوم: |
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