Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity
<p dir="ltr">Klotho, a well-known aging suppressor protein, has been implicated in neuroprotection and the regulation of neuronal senescence. While previous studies have demonstrated its anti-aging properties in human brain organoids, its potential to mitigate neurodegenerative proce...
Saved in:
| Main Author: | Mohammed R. Shaker (10316180) (author) |
|---|---|
| Other Authors: | Salam Salloum-Asfar (656363) (author), Rowaida Z. Taha (8854754) (author), Ibrahim Javed (3478850) (author), Ernst J. Wolvetang (10316186) (author) |
| Published: |
2025
|
| Subjects: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Deletion of TRPC6, an Autism Risk Gene, Induces Hyperexcitability in Cortical Neurons Derived from Human Pluripotent Stem Cells
by: Kyung Chul Shin (13913556)
Published: (2023) -
Characterization of a loss-of-function NSF attachment protein beta mutation in monozygotic triplets affected with epilepsy and autism using cortical neurons from proband-derived and CRISPR-corrected induced pluripotent stem cell lines
by: Gowher Ali (14152593)
Published: (2024) -
Upregulation of β-catenin due to loss of miR-139 contributes to motor neuron death in amyotrophic lateral sclerosis
by: Sophie Hawkins (18421377)
Published: (2022) -
Mitochondrial dysfunction: A notable contributor to the progression of Alzheimer's and Parkinson's disease
by: Abolaji Samson Olagunju (16855185)
Published: (2023) -
Screening for Novel Inhibitors of Amyloid Beta Aggregation and Toxicity as Potential Drugs for Alzheimer’s Disease
by: Sanaa Sharari (12561952)
Published: (2023)