CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriers

CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriers

<h3>Background</h3><p dir="ltr">Asymptomatic carriers of leucine-rich repeat kinase 2 (LRRK<sub>2</sub>) gene mutations constitute an ideal population for discovering prodromal biomarkers of Parkinson’s disease (PD). In this study, we aim to identify CSF candi...

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Bibliographic Details
Main Author: Nour K. Majbour (8809316) (author)
Other Authors: Jan O. Aasly (7930109) (author), Eldbjørg Hustad (8809319) (author), Mercy A. Thomas (8809322) (author), Nishant N. Vaikath (2901785) (author), Naser Elkum (79418) (author), Wilma D. J. van de Berg (8809325) (author), Takahiko Tokuda (105837) (author), Brit Mollenhauer (482499) (author), Henk W. Berendse (8809328) (author), Omar M. A. El-Agnaf (8809331) (author)
Published: 2020
Subjects:
Biomedical and clinical sciences
Clinical sciences
Neurosciences
Parkinson’s disease
LRRK2 mutation carriers
Alpha-synuclein oligomers
Biomarkers
Inflammatory markers
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