Evaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation

Evaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation

<p>Patients treated during leukemia face the risk of complications including pulmonary dysfunction that may result from infiltration of leukemic blast cells (LBCs) into lung parenchyma and interstitium. In LBCs, we demonstrated that transient receptor potential vanilloid type 2 channel (TRPV2)...

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Bibliographic Details
Main Author: Kodappully S. Siveen (4246150) (author)
Other Authors: Kirti S. Prabhu (4246144) (author), Aeijaz S. Parray (14152734) (author), Maysaloun Merhi (4246147) (author), Abdelilah Arredouani (10914455) (author), Mohamed Chikri (2243) (author), Shahab Uddin (154400) (author), Said Dermime (79420) (author), Ramzi M. Mohammad (14152737) (author), Martin Steinhoff (5340194) (author), Ibrahim A. Janahi (14070765) (author), Fouad Azizi (14152740) (author)
Published: 2019
Subjects:
Biomedical and clinical sciences
Clinical sciences
Oncology and carcinogenesis
Leukemia
Leukemic Blast Cells (LBCs)
Oncogenic Activity
Molecular Expression
Pulmonary Dysfunction
Airway Inflammation
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