MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the SMAD2/TGFβ pathway

MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the SMAD2/TGFβ pathway

<p dir="ltr">MicroRNAs (miRs/miRNAs) play a key role in posttranscriptional regulation of gene expression and are implicated in a number of physiological and pathological conditions, including cellular malignant transformation. In the current study, we investigated the role of miR-31...

Full description

Saved in:
Bibliographic Details
Main Author: Radhakrishnan Vishnubalaji (3563306) (author)
Other Authors: Ramesh Elango (7542068) (author), Muthurangan Manikandan (6002243) (author), Abdul-Aziz Siyal (18619237) (author), Dalia Ali (6002237) (author), Ammar Al-Rikabi (5213753) (author), Dana Hamam (3400181) (author), Rimi Hamam (3563312) (author), Hicham Benabdelkamel (2094556) (author), Afshan Masood (8279052) (author), Ibrahim O. Alanazi (3219180) (author), Assim A. Alfadda (9674998) (author), Musaad Alfayez (3571736) (author), Abdullah Aldahmash (3563300) (author), Moustapha Kassem (101848) (author), Nehad M. Alajez (7397276) (author)
Published: 2020
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Clinical sciences
Medical biotechnology
Oncology and carcinogenesis
MicroRNAs
Stem Cells
miR-3148
Adipocytic Differentiation
Carcinogenesis
Sarcoma
Proteomic Analysis
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items