Computational formulation of a multiepitope vaccine unveils an exceptional prophylactic candidate against Merkel cell polyomavirus

Computational formulation of a multiepitope vaccine unveils an exceptional prophylactic candidate against Merkel cell polyomavirus

<p dir="ltr">Merkel cell carcinoma (MCC) is a rare neuroendocrine skin malignancy caused by human Merkel cell polyomavirus (MCV), leading to the most aggressive skin cancer in humans. MCV has been identified in approximately 43%–100% of MCC cases, contributing to the highly aggressiv...

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Bibliographic Details
Main Author: Raihan Rahman Imon (9286530) (author)
Other Authors: Abdus Samad (4388131) (author), Rahat Alam (9286527) (author), Ahad Amer Alsaiari (13902165) (author), Md. Enamul Kabir Talukder (15219826) (author), Mazen Almehmadi (10047618) (author), Foysal Ahammad (9286524) (author), Farhan Mohammad (256409) (author)
Published: 2023
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Immunology
Oncology and carcinogenesis
Merkel cell polyomavirus (MCV)
Merkel cell carcinomas (MCC)
immunoinformatics
vaccine design
multiepitope vaccine
molecular dynamics simulation (MD)
molecular docking
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