Natural resorcylic acid lactones: A chemical biology approach for anticancer activity

Natural resorcylic acid lactones: A chemical biology approach for anticancer activity

<p dir="ltr">Resorcylic acid lactones (RALs) are fungal polyketides that consist of a β-resorcylic acid residue (2,4-dihydroxybenzoic acid) embedded in a macrolactone ring. RALs exhibit a broad range of biological activities, including anticancer activities. Following discovery of th...

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Bibliographic Details
Main Author: Shilpa Kuttikrishnan (3520079) (author)
Other Authors: Kirti S. Prabhu (4246144) (author), Ahmed H. Al Sharie (9650242) (author), Yazan O. Al Zu'bi (17191321) (author), Feras Q. Alali (2691907) (author), Nicholas H. Oberlies (326437) (author), Aamir Ahmad (233201) (author), Tamam El-Elimat (694398) (author), Shahab Uddin (154400) (author)
Published: 2022
Subjects:
Biomedical and clinical sciences
Medical biochemistry and metabolomics
Oncology and carcinogenesis
Pharmacology and pharmaceutical sciences
Resorcylic acid lactones
Heat shock protein 90 inhibitors
Protein kinase inhibitors
Radicicol
Hypothemycin
5Z-7-oxo-zeaenol
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