Single-cell transcriptomics identifies master regulators of neurodegeneration in SOD1 ALS iPSC-derived motor neurons
<p>Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative condition characterized by the loss of motor neurons. We utilized single-cell transcriptomics to uncover dysfunctional pathways in degenerating motor neurons differentiated from SOD1 E100G ALS patient-derived induced pluripote...
محفوظ في:
| المؤلف الرئيسي: | Seema C. Namboori (11031624) (author) |
|---|---|
| مؤلفون آخرون: | Patricia Thomas (3489989) (author), Ryan Ames (3486263) (author), Sophie Hawkins (18421377) (author), Lawrence O. Garrett (18589426) (author), Craig R.G. Willis (18589429) (author), Alessandro Rosa (470248) (author), Lawrence W. Stanton (6707191) (author), Akshay Bhinge (173004) (author) |
| منشور في: |
2021
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| الموضوعات: | |
| الوسوم: |
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