Anti-hypertrophic effect of Na<sup>+</sup>/H<sup>+</sup> exchanger-1 inhibition is mediated by reduced cathepsin B

Anti-hypertrophic effect of Na<sup>+</sup>/H<sup>+</sup> exchanger-1 inhibition is mediated by reduced cathepsin B

<p dir="ltr">Previous studies have established the role of Na<sup>+</sup>/H<sup>+</sup> exchanger isoform-1 (NHE1) and cathepsin B (Cat B) in the development of cardiomyocyte hypertrophy (CH). Both NHE1 and Cat B are activated under acidic conditions suggestin...

Full description

Saved in:
Bibliographic Details
Main Author: Sadaf Riaz (6016985) (author)
Other Authors: Nabeel Abdulrahman (725914) (author), Shahab Uddin (154400) (author), Ayesha Jabeen (5438063) (author), Alain P. Gadeau (17100208) (author), Larry Fliegel (700859) (author), Fatima Mraiche (715733) (author)
Published: 2020
Subjects:
Biomedical and clinical sciences
Neurosciences
Pharmacology and pharmaceutical sciences
Cardiomyocytes
Hypertrophy
Autophagy
Cathepsins
Angiotensin
Matrix metalloproteinases
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items