Transgelin is a poor prognostic factor associated with advanced colorectal cancer (CRC) stage promoting tumor growth and migration in a TGFβ-dependent manner

Transgelin is a poor prognostic factor associated with advanced colorectal cancer (CRC) stage promoting tumor growth and migration in a TGFβ-dependent manner

<p dir="ltr">Colorectal cancer (CRC) is the fourth most common cancer type globally. Investigating the signaling pathways that maintain cancer cell phenotype can identify new biomarkers for targeted therapy. Aberrant transforming growth factor-β (TGFβ) signaling has been implicated i...

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Bibliographic Details
Main Author: Mona Elsafadi (18614905) (author)
Other Authors: Muthurangan Manikandan (6002243) (author), Sami Almalki (18949444) (author), Amer Mahmood (284424) (author), Tasneem Shinwari (18614908) (author), Radhakrishnan Vishnubalaji (3563306) (author), Mohammad Mobarak (18949447) (author), Musaad Alfayez (3571736) (author), Abdullah Aldahmash (3563300) (author), Moustapha Kassem (101848) (author), Nehad M. Alajez (7397276) (author)
Published: 2020
Subjects:
Biological sciences
Biochemistry and cell biology
Biomedical and clinical sciences
Oncology and carcinogenesis
Colorectal cancer (CRC)
Transforming growth factor-β (TGFβ)
TAGLN (Transgelin)
Prognostic marker
Biomarker
Tumor progression
Angiogenesis
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