Network-based identification of key master regulators associated with an immune-silent cancer phenotype

Network-based identification of key master regulators associated with an immune-silent cancer phenotype

<div><p>A cancer immune phenotype characterized by an active T-helper 1 (Th1)/cytotoxic response is associated with responsiveness to immunotherapy and favorable prognosis across different tumors. However, in some cancers, such an intratumoral immune activation does not confer protection...

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Bibliographic Details
Main Author: Raghvendra Mall (581171) (author)
Other Authors: Mohamad Saad (214545) (author), Jessica Roelands (7516439) (author), Darawan Rinchai (742366) (author), Khalid Kunji (828224) (author), Hossam Almeer (9771875) (author), Wouter Hendrickx (44559) (author), Francesco M Marincola (808) (author), Michele Ceccarelli (184154) (author), Davide Bedognetti (2632474) (author)
Published: 2021
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Oncology and carcinogenesis
transcription regulator
master regulator analysis
immunologic constant of rejection
immune exclusion
gene regulatory networks
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