DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression

DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression

<p dir="ltr">Heat shock response (HSR) is an essential host-defense mechanism that is dysregulated in obesity-induced insulin resistance and type 2 diabetes (T2D). Our recent data demonstrated that DNAJB3 was downregulated in obese human subjects and showed negative correlation with...

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Bibliographic Details
Main Author: Mohamed Abu-Farha (25322) (author)
Other Authors: Preethi Cherian (437070) (author), Irina Al-Khairi (437069) (author), Ali Tiss (437068) (author), Abdelkrim Khadir (437074) (author), Sina Kavalakatt (437073) (author), Samia Warsame (437075) (author), Mohammed Dehbi (309033) (author), Kazem Behbehani (412126) (author), Jehad Abubaker (437067) (author)
Published: 2015
Subjects:
Biomedical and clinical sciences
Medical biochemistry and metabolomics
Heat Shock Response (HSR)
Insulin Resistance
Type 2 Diabetes (T2D)
DNAJB3
Obesity Inflammatory Markers
Gene Expression
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