Genome‐wide DNA methylation analysis of colorectal adenomas with and without recurrence reveals an association between cytosine‐phosphate‐guanine methylation and histological subtypes

Genome‐wide DNA methylation analysis of colorectal adenomas with and without recurrence reveals an association between cytosine‐phosphate‐guanine methylation and histological subtypes

<div><p>Aberrant methylation of DNA is supposed to be a major and early driver of colonic adenoma development, which may result in colorectal cancer (CRC). Although gene methylation assays are used already for CRC screening, differential epigenetic alterations of recurring and nonrecurri...

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Bibliographic Details
Main Author: David Fiedler (2672563) (author)
Other Authors: Daniela Hirsch (7317635) (author), Nady El Hajj (686554) (author), Howard H. Yang (10746217) (author), Yue Hu (201714) (author), Carsten Sticht (104859) (author), Indrajit Nanda (226370) (author), Sebastian Belle (5534465) (author), Josef Rueschoff (18200575) (author), Maxwell P. Lee (8808563) (author), Thomas Ried (48620) (author), Thomas Haaf (342924) (author), Timo Gaiser (745318) (author)
Published: 2019
Subjects:
Biological sciences
Genetics
adenoma
DNA methylation
epigenetics
histological subtype
recurrence
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