B7-H3 at the crossroads between tumor plasticity and colorectal cancer progression: a potential target for therapeutic intervention

B7-H3 at the crossroads between tumor plasticity and colorectal cancer progression: a potential target for therapeutic intervention

<p dir="ltr">B7-H3 (B7 homology 3 protein) is an important transmembrane immunoregulatory protein expressed in immune cells, antigen-presenting cells, and tumor cells. Studies reveal a multifaceted role of B7-H3 in tumor progression by modulating various cancer hallmarks involving an...

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Bibliographic Details
Main Author: Elizabeth Varghese (11008845) (author)
Other Authors: Samson Mathews Samuel (11008848) (author), Aranka Brockmueller (11064675) (author), Mehdi Shakibaei (325455) (author), Peter Kubatka (11008854) (author), Dietrich Büsselberg (11008857) (author)
Published: 2023
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Immunology
Oncology and carcinogenesis
Colorectal cancer
B7-H3
Immunomodulation
Tumor plasticity, immune checkpoint
Drug resistance
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