Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice

<p>Matrix metalloproteinase-8 (MMP-8; neutrophil collagenase) is an important regulator of innate immunity that has oncosuppressive actions in numerous tumor types. We have intercrossed Mmp8-null mice with the Polyoma virus middle T oncogene-driven (MMTV-PyMT) mouse model of mammary cancer to...

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Bibliographic Details
Main Author: Julie Decock (44558) (author)
Other Authors: Wouter Hendrickx (44559) (author), Sally Thirkettle (702179) (author), Ana Gutiérrez-Fernández (72539) (author), Stephen D Robinson (16210301) (author), Dylan R Edwards (19651870) (author)
Published: 2015
Subjects:
Biological sciences
Genetics
Biomedical and clinical sciences
Clinical sciences
Immunology
Oncology and carcinogenesis
Skin Papilloma
PyMT Mouse
Skin Squamous Cell Carcinoma
TIMP Family
Mmp8 Genotype
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