RT-QuIC Using C-Terminally Truncated α-Synuclein Forms Detects Differences in Seeding Propensity of Different Brain Regions from Synucleinopathies
<div><p>Aggregated α-synuclein (αSyn) protein is a core pathological feature of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Both PD and DLB demonstrate the presence of diverse intracellular α-synuclein (αSyn) species, including C-terminally truncated αSyn (C-αSyn), alth...
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| Main Author: | Ilaria Poggiolini (296742) (author) |
|---|---|
| Other Authors: | Daniel Erskine (3471959) (author), Nishant N. Vaikath (2901785) (author), Janarthanan Ponraj (8535585) (author), Said Mansour (8697699) (author), Christopher M. Morris (741292) (author), Omar M. A. El-Agnaf (8809331) (author) |
| Published: |
2021
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| Subjects: | |
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