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<div><p>RNA-binding proteins (RBPs) regulate translation and plasticity which are required for memory. RBP dysfunction has been linked to a range of neurological disorders where cognitive impairments are a key symptom. However, of the 2,000 RBPs in the human genome, many are uncharacteri...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Ashley N. Hayden (19871128) (author)
مؤلفون آخرون:	Katie L. Brandel (19871131) (author), Edward W. Pietryk (5777888) (author), Paul R. Merlau (19871134) (author), Priyadharshini Vijayakumar (19871137) (author), Emily J. Leptich (19871140) (author), Elizabeth S. Gaytan (19871143) (author), Meredith I. Williams (19871146) (author), Connie W. Ni (19871149) (author), Hsiao-Tuan Chao (4454008) (author), Jill A. Rosenfeld (9606199) (author), Rachel N. Arey (19871152) (author)
منشور في:	2024
الموضوعات:	Biochemistry Neuroscience Pharmacology Evolutionary Biology Immunology Cancer Mental Health Infectious Diseases Biological Sciences not elsewhere classified test evolutionary conservation single nucleotide variants potential new source behavioral screening reveals potential functional significance leveraging human datasets ></ u >< reveal memory regulators div >< p x </ u b </ u identifies ybx dysfunction binding protein required 20 conserved rbps u >< unknown significance rbp dysfunction human genome conserved residue binding proteins ybxs </ ybx3 </ legans </ elegans </ e </ c </ 3 </ study highlights regulate translation rbp family promote memory neurological symptoms neurological phenotypes neurological disorders nervous system memory ability key symptom functionally replace cognitive impairments closest ortholog associative learning 000 rbps
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