Characterization of selected G-rich sequences from the IAV genome.

<p>Characterization of selected G-rich sequences from the IAV genome.</p>

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Maria Nalewaj (22647898) (author)
مؤلفون آخرون:	Joanna Sliwiak (18006655) (author), Karolina Zielinska (22647901) (author), Pawel Zmora (797085) (author), Dorota Niedziałek (18087212) (author), Grzegorz Wieczorek (18087215) (author), Elzbieta Kierzek (27228) (author), Marta Szabat (241215) (author)
منشور في:	2025
الموضوعات:	Biophysics Biochemistry Microbiology Biotechnology Cancer Infectious Diseases Virology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified uv melting analysis type g4 variants promising antiviral targets one variant exhibiting global public health commonly used g4 revealing significant inhibition iav minireplicon activity various structural motifs g4 binding ligands three selected g4s structural stability binding properties binding affinity xlink "> thermal stability specific ligands serious threat rna g4s rich sequences results showed potential anti molecular modeling limited range iav replication iav g4s fluorescence spectroscopy experimental approaches crucial role compounds inhibited circular dichroism cdna synthesis also examined
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