Concentrations of serotype-specific pneumococcal IgA antibodies for Indigenous (n = 77) and non-Indigenous groups (n = 64).

<p>Geometric mean antibody concentrations are displayed (μg/ mL) and the 95% confidence intervals of the GMC. Statistical significance was determined using a Mann-Whitney U test for all serotypes. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.</p>

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Gabrielle N. Gaultier (5634923) (author)
مؤلفون آخرون:	Eli B. Nix (12418705) (author), Joelle Thorgrimson (5634926) (author), Douglas Boreham (5634935) (author), William McCready (7858295) (author), Marina Ulanova (5634938) (author)
منشور في:	2022
الموضوعات:	Medicine Microbiology Cell Biology Ecology Immunology Cancer Infectious Diseases Biological Sciences not elsewhere classified streptococcus pneumoniae </ naturally acquired antibodies experience high burden div >< p determining serological correlates pneumococcal conjugate vaccines adult pneumococcal immunizations 141 healthy individuals indigenous study participants canadian indigenous people protect unvaccinated adults specific capsular polysaccharides indigenous individuals suggesting striking differences found natural serum igg generally higher concentrations iga antibodies specific 23f significantly decreased 7 common serotypes indigenous adults concentrations indigenous individuals significantly higher natural igg specific iga pneumococcal infections indigenous adults igg specific indigenous residing analysed concentrations young children unlikely related reactive antigens potentially associated plants present pediatric immunization major reservoir likely attributed life span larger exposure increased rates increased exposure geographical area data suggest
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Concentrations of serotype-specific pneumococcal IgA antibodies for Indigenous (n = 77) and non-Indigenous groups (n = 64).

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