Data Sheet 1_Genetic manipulation of bacteriophage T4 utilizing the CRISPR-Cas13b system.pdf
<p>CRISPR-Cas type II and type V systems are inefficient in modifying bacteriophage T4 genome, due to hypermodification of its DNA. Here, we present a genome editing technique for bacteriophage T4 using the type VI CRISPR-Cas system. Using BzCas13b targeting of T4 phage, we were able to indivi...
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2024
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