Annotated differentially expressed genes in TIGIT<sup>+</sup>PD-1<sup>−</sup>CD8<sup>+</sup> T cell subset compared to the TIGIT<sup>−</sup>PD-1<sup>−</sup> subset.

Annotated differentially expressed genes in TIGIT<sup>+</sup>PD-1<sup>−</sup>CD8<sup>+</sup> T cell subset compared to the TIGIT<sup>−</sup>PD-1<sup>−</sup> subset.

<p>Annotated differentially expressed genes in TIGIT<sup>+</sup>PD-1<sup>−</sup>CD8<sup>+</sup> T cell subset compared to the TIGIT<sup>−</sup>PD-1<sup>−</sup> subset.</p>

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Bibliographic Details
Main Author:	Jingyu Zhou (7859525) (author)
Other Authors:	Qingluan Yang (10776420) (author), Haoxin Xu (18870514) (author), Huaxin Chen (38442) (author), Ning Jiang (118848) (author), Qinfang Ou (7496645) (author), Mengqing Qian (18870511) (author), Xing Lin (534240) (author), Yixuan Yang (510257) (author), Feiran Zhou (9045552) (author), Yuzhen Xu (11897984) (author), Qianqian Liu (381114) (author), Yuanyuan Liu (136992) (author), Yan Gao (93649) (author), Wenhong Zhang (207387) (author), Lingyun Shao (207377) (author), Qiaoling Ruan (594716) (author)
Published:	2025
Subjects:	Biochemistry Microbiology Cell Biology Molecular Biology Immunology Cancer Hematology Infectious Diseases Biological Sciences not elsewhere classified sup >+</ sup kill intracellular bacteria investigated whether blocking div >< p produce effector molecules findings also suggest tuberculosis mouse model tigit blockade increased implicate tigit blockade increased expression levels clinical features analyzed immune checkpoint blockade mycobacterium tuberculosis </ cells express tigit active tuberculosis patients tigit blockade immune checkpoint tigit expression tuberculosis </ findings reveal differentiation levels cytotoxic molecules tuberculosis patients tigit limits pulmonary tuberculosis vivo </ vitro </ transcriptome analysis therapeutic benefit significantly upregulated significantly higher promotes clearance positively correlated peripheral blood patients infected novel strategy natural killer mice infected lung lesions infectious diseases immunoreceptor tyrosine functional status flow cytometry disease severity cell subsets cell immunoreceptor bacterial load
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