Deciphering RIN3's Role in Alzheimer’s Disease Pathogenesis: A Focus on Endocytic Dysregulation and Early Neurodegeneration

<p dir="ltr">RIN3, a guanine nucleotide exchange factor (GEF), has emerged as a potential contributor to Alzheimer’s disease (AD) pathogenesis through its role in regulating endocytic trafficking and neuronal signaling. By interacting with Rab proteins, particularly Rab5, RIN3 may in...

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التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Jiyeon Song (5571476) (author)
مؤلفون آخرون:	Crystal Zhang (1958683) (author), Natalie Kim (22353697) (author), Brian Lee (2978367) (author), Zahraa Munaim (22353700) (author), Daniel Park (249278) (author), Dennie Gutierrez (22353701) (author), Anyi Wang (9595097) (author), Nathan Teerlink (22353703) (author), Linda Z. Shi (19183704) (author), Chengbiao Wu (12863681) (author), Kijung Sung (542575) (author)
منشور في:	2025
الموضوعات:	Cell neurochemistry RIN3 protein Alzheimer’s disease (AD) Endocytic trafficking Rab5 NeuN marker Hippocampus Cellpose analysis Neuronal nuclei Neurodegeneration Machine learning in bioimaging
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Deciphering RIN3's Role in Alzheimer’s Disease Pathogenesis: A Focus on Endocytic Dysregulation and Early Neurodegeneration

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