Detection limit experiment to evaluate Hi-C linkages in varied concentration SynCom-2 and SynCom-3.

A. All Z-scores (left) and virus-host linkages (right) for each replicate of SynCom-2, categorized by host strains. All figure elements are the same as described in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.300351...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Rokaiya Nurani Shatadru (22656316) (author)
مؤلفون آخرون:	Natalie E. Solonenko (5280548) (author), Christine L. Sun (22656319) (author), Matthew B. Sullivan (7419248) (author)
منشور في:	2025
الموضوعات:	Microbiology Ecology Infectious Diseases Virology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified viruses increasingly appear understudied viral taxa synthetic communities provides relative low resolution natural soil samples minimal phage abundances impose key constraints expanded genomic catalogs >- score thresholding host linkage studies host genomic fragments predictions – particularly least 10 studies div >< p c sample preparations accuracy remains unknown host linkages inferred 15 %) levels specificity ), though based bioinformatic approaches 5 </ sup host linkages retained ), bioinformatic methods based approaches 43 %) host interactions host inferences host identification z </ silico </ family levels ≥ 0 studied climate scaling cultivation respectively ). relatively high predictions generated nine phages modest improvements methodological guidelines machine learning known interactions incorrect matches dramatically improved detection limits critical soils c sequencing c performance c alone
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Detection limit experiment to evaluate Hi-C linkages in varied concentration SynCom-2 and SynCom-3.

مواد مشابهة