Changing and stable fitness landscapes.

<p>(A & B) For a given codon position of a protein-coding DNA sequence, amino acids (x-axis) have different fitness values (y-axis). Under a changing fitness landscape (A), these fitnesses fluctuate with time. The protein sequence follows the moving target defined by the amino-acid fitness...

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Bibliographic Details
Main Author:	Thibault Latrille (4514248) (author)
Other Authors:	Julien Joseph (20477553) (author), Diego A. Hartasánchez (8822762) (author), Nicolas Salamin (2923683) (author)
Published:	2024
Subjects:	Genetics Evolutionary Biology Ecology Cancer Infectious Diseases Biological Sciences not elsewhere classified widely neglected mainly typically unpredictable since indeed positively selected 28 populations analyzed 28 mammalian populations ongoing positive selection underlying fitness landscape xlink "> mutations adaptive mutations represent mammals </ p extant populations selection models quantify selection higher fitness fitness landscapes fitness effect adaptive mutations work confirms using mutation using methods unforeseen change substantial part simply restoring restored simultaneously reconstructed protein population level polymorphisms found molecular evolution lost due genetic drift environmental change driven solely different loci deleterious substitutions bringing innovation allowed us
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Changing and stable fitness landscapes.

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