Terminal bacterial burden in animals infected with Bcbva. Animals that succumbed to infection in the LD₅₀ studies (n = 23 for CA; n = 25 for CI) were sampled, and mean CFU/ml or g determined for blood, BAL, liver, lung, and spleen tissues. Six survivors were sampled as controls and bacteria were not observed in any of the assayed tissues or fluids at 28 days post-exposure. Data shown are mean with lower and upper 95% confidence intervals in brackets.

مواد مشابهة

• Terminal bacterial burden in animals that succumbed following the cessation of levofloxacin treatment and non-treated controls.
  حسب: Allison M. Ferris (21011700)
  منشور في: (2025)
• Summary of MCM efficacy and outcomes following Bcbva CA or CI aerosol exposure. MCM were administered as described in Materials and Methods. *Indicates animal succumbed immediately after treatment. Animal data was censored. ^#Indicates a telemetry transponder failed, and no temperature data was collected. ^βIndicates SIBT occurred following completion of treatment course. ^{^}Indicates quantified values were not statistically different than pre-administration samples via pair-wise comparison. NA indicates not applicable. ^†Indicates seroconversion occurred before exposure.
  حسب: Allison M. Ferris (21011700)
  منشور في: (2025)
• Quantification of virulence factors in MCM-treated animals following aerosol exposure to Bcbva CA and CI.
  حسب: Allison M. Ferris (21011700)
  منشور في: (2025)
• Dose-dependent median time to death following inhalation exposure to Bcbva CA and CI. Log-Rank Mantel Cox Test was performed to identify differences in time to death among the administered doses. Data were derived from 8 animals per dose of Bcbva CA and CI and 10 animals for Ames A2084. Since multiple deaths/dose group are required to determine a median time to death, only the data for those doses are listed. The <i>B. anthracis</i> data were derived from a previous study [25]. Since dose does not influence time to death for <i>B. anthracis</i> challenge, the dose range and mean time to death are reported.
  حسب: Allison M. Ferris (21011700)
  منشور في: (2025)
• Colony morphologies of Bcbva.
  حسب: Allison M. Ferris (21011700)
  منشور في: (2025)