Variant-specific serum reactivity in the Ig class capture NTD-EIA.

(a) IgA reactivity, (b) IgG reactivity. Sera were tested at a dilution of 1:100. The means of two independent experiments are shown. Antibody reactivity is given in relative light units (rlu). Values below 0 rlu were set to zero. The cut-off was set at...

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Main Author:	Michael Schoefbaenker (19852510) (author)
Other Authors:	Theresa Günther (19852513) (author), Eva Ulla Lorentzen (19852516) (author), Marie-Luise Romberg (19852519) (author), Marc Tim Hennies (19852522) (author), Rieke Neddermeyer (19852525) (author), Marlin Maybrit Müller (19852528) (author), Alexander Mellmann (72273) (author), Chiara Robin Bojarzyn (19852531) (author), Georg Lenz (447872) (author), Matthias Stelljes (106772) (author), Eike Roman Hrincius (19852534) (author), Richard Vollenberg (11228718) (author), Stephan Ludwig (142429) (author), Phil-Robin Tepasse (11228730) (author), Joachim Ewald Kühn (19852537) (author)
Published:	2024
Subjects:	Medicine Microbiology Evolutionary Biology Ecology Immunology Cancer Mental Health Infectious Diseases Virology Computational Biology situation temporarily favouring one year later apparent genetic stability specific immune response routine serology revealed receptor binding domain immunocompromised patient coincided following bamlanivimab treatment escape mutations changed although virus elimination escape mutations virus elimination terminal domain routine diagnosis escape mutants additional mutations unprecedented dynamic ultimately achieved triple mutant short period resistant virus resistant mutation reactive antibodies protective immunity patient developed neutralising antibodies major determinants host evolution five weeks early stage detailed analysis deletions within cell depleted antibody response additional substitutions
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Variant-specific serum reactivity in the Ig class capture NTD-EIA.

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