qPCR validation of DEGs and functional assays.

<p><b>(A)</b> qPCR validation of DEGs identified through CytoHubba and MCODE analysis in the PPI network. Among the six hub genes, except for C3 which showed no statistical difference, CLEC4E, CSF3R, CXCR2, and FPR2 were upregulated in the disease group compared to the control grou...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Chen Chen (6544) (author)
مؤلفون آخرون:	Zhuojing Hu (22211125) (author), Yunbo Ma (499277) (author), Qinghua Xia (281716) (author), Zheng Ma (351144) (author), Jiangsong Li (14834980) (author), Wei Zhao (14321) (author)
منشور في:	2025
الموضوعات:	Cell Biology Genetics Molecular Biology Immunology Biological Sciences not elsewhere classified Information Systems not elsewhere classified underlying molecular mechanisms underactive bladder based tgf -&# 946 receiver operating characteristic differential expression patterns bacterial defense responses twelve key genes functional enrichment analysis 12 key genes validation set compared gene expression omnibus degs ), followed 1 treated sv validation dataset gse28242 promising diagnostic biomarkers curve analysis demonstrated potential therapeutic targets drug interaction network therapeutic targets potential biomarkers hub genes bioinformatics analysis validation confirmed hub gene five degs experimental validation drug discovery diagnostic value 1 cells interaction network values greater transcription factor study aims regulatory network quantitative real mirna co mcode plugins gse100219 datasets geo dataset five tfs findings suggest effective management control group common disorder cell chemotaxis bioinformatics analyses
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qPCR validation of DEGs and functional assays.

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