Schematic overview of a pig farm and the three hypothesized environmental transmission routes (indicated by pink arrows) of hepatitis E virus in farms.

Schematic overview of a pig farm and the three hypothesized environmental transmission routes (indicated by pink arrows) of hepatitis E virus in farms.

<p>Schematic overview of a pig farm and the three hypothesized environmental transmission routes (indicated by pink arrows) of hepatitis E virus in farms.</p>

Wedi'i Gadw mewn:

Manylion Llyfryddiaeth
Prif Awdur:	Marina Meester (11765542) (author)
Awduron Eraill:	Cecilia Valenzuela Agüí (22676709) (author), Tijs J. Tobias (9582206) (author), Claire Guinat (3184698) (author), Martijn Bouwknegt (2620273) (author), Louis du Plessis (3264087) (author), Egil A.J. Fischer (19205508) (author), Mirlin Spaninks (4405027) (author), Tanja Stadler (118822) (author), Wim H.M. van der Poel (11765557) (author), Arjan Stegeman (199275) (author)
Cyhoeddwyd:	2025
Pynciau:	Biotechnology Ecology Cancer Science Policy Infectious Diseases Virology Biological Sciences not elsewhere classified retrieving 89 near effective reproduction number eating contaminated pork consecutively housed groups observed phylogenetic clustering integrated epidemiological data making hev control hev &# 8217 sequenced per batch pig farms crucial many pig farms zoonotic risk may pigs housed separately hpd interval 1 hepatitis e virus div >< p 3 &# 8211 pens tested positive pens per compartment investigated hev transmission hev transmission dynamics zoonotic virus phylogenetic data batch may causes hepatitis remained hev hev persists one batch pens within transmission routes suggesting transmission quantify transmission pen transmission enabling transmission public health positive pen pigs separated pigs ). nine months negative thanks genotype 3 findings show findings reveal environmental routes become infected 7 ).
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg

Infection dynamics and phylogenetics of HEV in two farms.
gan: Marina Meester (11765542)
Cyhoeddwyd: (2025)

Maximum clade credibility (MCC) trees of phylodynamic models for transmission in farm A.
gan: Marina Meester (11765542)
Cyhoeddwyd: (2025)

Output of phylodynamic (BD) and SEIR model to estimate the effective reproduction number of between-pen transmission (between-pen R<sub>e</sub>) for farm B, compartment 2 during weeks 7 to 16 of batch B.
gan: Marina Meester (11765542)
Cyhoeddwyd: (2025)

The simulation parameters.
gan: Ziyang Xing (22683634)
Cyhoeddwyd: (2025)

Convergence normalization comparison.
gan: Ziyang Xing (22683634)
Cyhoeddwyd: (2025)

Throughput normalization comparison of several algorithms under different transmission conditions.
gan: Ziyang Xing (22683634)
Cyhoeddwyd: (2025)

Principle of expert library reinforcement learning designed.
gan: Ziyang Xing (22683634)
Cyhoeddwyd: (2025)

Data transmission scenario diagram in integrated network.
gan: Ziyang Xing (22683634)
Cyhoeddwyd: (2025)

Data Sheet 2_Genomic analysis reveals genetic diversity and selection signatures of the Yantai Black pig during domestication and breeding.xlsx
gan: Ming Qin (1737352)
Cyhoeddwyd: (2025)

Data Sheet 1_Genomic analysis reveals genetic diversity and selection signatures of the Yantai Black pig during domestication and breeding.docx
gan: Ming Qin (1737352)
Cyhoeddwyd: (2025)

Extended Data Figure 4 – Source Data (sEPSC properties after sub-chronic ketamine)
gan: Jinseon Yu (22598699)
Cyhoeddwyd: (2025)

Filamin A KO and S2152A KI reduce cell migration under ORF45 overexpression or during KSHV de novo infection or lytic reactivation.
gan: Xiaojuan Li (351842)
Cyhoeddwyd: (2025)

Filamin A KO and S2152A KI reduce KSHV de novo infection and cell-contact mediated viral infection.
gan: Xiaojuan Li (351842)
Cyhoeddwyd: (2025)

Filamin A KO and S2152A KI reduce KSHV de novo infection of cell-free virions.
gan: Xiaojuan Li (351842)
Cyhoeddwyd: (2025)

Filamin A phosphorylation is essential for ORF45-induced detachment and migration but not for virion production.
gan: Xiaojuan Li (351842)
Cyhoeddwyd: (2025)

ORF45 promotes cell migration during early primary infection.
gan: Xiaojuan Li (351842)
Cyhoeddwyd: (2025)

ORF45 reduces cell adhesion through RSK activation.
gan: Xiaojuan Li (351842)
Cyhoeddwyd: (2025)

Filamin A phosphorylation is induced by ORF45-mediated RSK activation.
gan: Xiaojuan Li (351842)
Cyhoeddwyd: (2025)

The expression levels of Filamin A in KSHV-positive cells.
gan: Xiaojuan Li (351842)
Cyhoeddwyd: (2025)

Filamin A KO and S2152A KI in donor cells do not affect KSHV cell-to-cell viral transmission.
gan: Xiaojuan Li (351842)
Cyhoeddwyd: (2025)

Filamin A KO or S2152A KI does not affect KSHV lytic reactivation.
gan: Xiaojuan Li (351842)
Cyhoeddwyd: (2025)

Validation of Filamin A KO and S2152A KI stable HEK293-mcherry cells.
gan: Xiaojuan Li (351842)
Cyhoeddwyd: (2025)

The treatment of RSK inhibitors attenuates ORF45-increased ability of cell migration.
gan: Xiaojuan Li (351842)
Cyhoeddwyd: (2025)

RSK inhibitors suppress ORF45-induced Filamin A phosphorylation.
gan: Xiaojuan Li (351842)
Cyhoeddwyd: (2025)

Microscopic agglutination test results.
gan: Paul Le Turnier (7829654)
Cyhoeddwyd: (2025)

Occupational and other individual exposure factors.
gan: Paul Le Turnier (7829654)
Cyhoeddwyd: (2025)

Water collection sources and usages.
gan: Paul Le Turnier (7829654)
Cyhoeddwyd: (2025)

Sociodemographic data and residence characteristics.
gan: Paul Le Turnier (7829654)
Cyhoeddwyd: (2025)

Flow chart of participants in leptospirosis serological survey.
gan: Paul Le Turnier (7829654)
Cyhoeddwyd: (2025)

Figure 2 – Source Data (spontaneous synaptic transmission and intrinsic properties in dmPFC L2/3 neurons)
gan: Jinseon Yu (22598699)
Cyhoeddwyd: (2025)

Table 1_Dynamics of Vibrio ostreicida in Mytilus galloprovincialis through in vivo infections.docx
gan: Martina Leonessi (22686236)
Cyhoeddwyd: (2025)

Impact of different substitution rate category parameters on cluster inference in different mixture datasets.
gan: August Guang (9975678)
Cyhoeddwyd: (2025)

Proportion of clusters recovered between different mixtures of pol and wgs sequences and all wgs based on overlap coefficient, subset dataset.
gan: August Guang (9975678)
Cyhoeddwyd: (2025)

Proportion of clusters recovered between different mixtures of pol and wgs sequences and all wgs based on overlap coefficient, full dataset.
gan: August Guang (9975678)
Cyhoeddwyd: (2025)

Adjusted mutual information (AMI) boxplot between phylogenetic clustering of different mixtures of pol and wgs sequences and all wgs, subset dataset.
gan: August Guang (9975678)
Cyhoeddwyd: (2025)

Adjusted mutual information (AMI) boxplot between phylogenetic clustering of different mixtures of pol and wgs sequences and all wgs, full dataset.
gan: August Guang (9975678)
Cyhoeddwyd: (2025)

Scatter and line plots of cluster number and mean cluster size as wgs percentage in mixture increases, subset dataset.
gan: August Guang (9975678)
Cyhoeddwyd: (2025)

Scatter and line plots of cluster number and mean cluster size as wgs percentage in mixture increases, full dataset.
gan: August Guang (9975678)
Cyhoeddwyd: (2025)

Principle Coordinates Analysis (PCoA) projected onto 2 dimensions between pol-wgs mixtures and nFL genome, subset dataset
gan: August Guang (9975678)
Cyhoeddwyd: (2025)

Principle Coordinates Analysis (PCoA) projected onto 2 dimensions between pol-wgs mixtures and nFL genome, full dataset
gan: August Guang (9975678)
Cyhoeddwyd: (2025)

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