Illustrations of CA3 engram formation inducing selective inhibition.

<p><b>(A)</b> The engram formation in CA3 driven by DG induces selective inhibition. Inhibitory neurons activated by mossy fibers inhibit most of the excitatory neurons. The surviving excitatory neurons and the activated inhibitory neurons form a neural assembly through STDP. <b...

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Auteur principal:	Gyeongtae Kim (12046886) (author)
Autres auteurs:	Pilwon Kim (556499) (author)
Publié:	2025
Sujets:	Neuroscience Pharmacology Biological Sciences not elsewhere classified Information Systems not elsewhere classified specific neural assemblies representation allows us recent findings indicate offering testable predictions distinct memories compete detailed mechanisms underlying specific inhibition mediated global inhibition alone sparse distributed coding selective firing patterns formation remain elusive emphasizes heterosynaptic plasticity mechanism generates sparse stable pattern completion inhibitory neurons associate selective inhibition synaptic plasticity pattern separation engram formation simulations show results suggest parsimonious mechanism models fail excitatory neurons dynamics arising diverse forms distributed engrams dg ), crucial role accuracy compared
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Illustrations of CA3 engram formation inducing selective inhibition.

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