Figure 1 from Dissecting FAP<sup>+</sup> Cell Diversity in Pancreatic Cancer Uncovers an Interferon-Response Subtype of Cancer-Associated Fibroblasts with Tumor-Restraining Properties

Figure 1 from Dissecting FAP<sup>+</sup> Cell Diversity in Pancreatic Cancer Uncovers an Interferon-Response Subtype of Cancer-Associated Fibroblasts with Tumor-Restraining Properties

<p>FAP<sup>+</sup> mesenchymal subtypes populate the PDAC stroma and reflect mesenchymal heterogeneity of the healthy developing pancreas. <b>A,</b> Single-cell mRNA sequencing workflow depicting isolation and single-cell transcriptomics (droplet capture) of PDAC-derive...

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Bibliografski detalji
Glavni autor: Joshua Cumming (15136746) (author)
Daljnji autori: Parniyan Maneshi (21643714) (author), Mitesh Dongre (15136767) (author), Tala Alsaed (21643717) (author), Mohammad Javad Dehghan-Nayeri (21643720) (author), Agnes Ling (21643723) (author), Kristian Pietras (15255434) (author), Cedric Patthey (15136770) (author), Daniel Öhlund (14942626) (author)
Izdano: 2025
Teme:
Cancer
Tumor Biology
Methods and Technology
Gastrointestinal Cancers
Pancreatic cancer
Preclinical Models
Organoids
Single Cell Technologies
Tumor Microenvironment
Tumor-stromal cell interactions
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