Comparison of vIL-4, cIL-4 and cIL-13 amino acid similarity and predicted receptor interactions.

<p>Panels A-E are aligned on amino acid position. (A) Secondary structure probability of the vIL-4 amino acid sequence as predicted by JPRED2. (B) Positions of identical amino acids between indicated aligned sequence pairs. (C) Positions of predicted atomic interactions between indicated ligan...

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Bibliographische Detailangaben
1. Verfasser:	Jeremy D. Volkening (13030758) (author)
Weitere Verfasser:	Stephen J. Spatz (4341484) (author), Maricarmen Garcia (21772671) (author), Teresa A. Ross (2066359) (author), Daniel A. Maekawa (21772674) (author), Kenneth S. Rosenthal (21772677) (author), Ana C. Zamora (21772680) (author), April Skipper (21772683) (author), Julia R. Blakey (21772686) (author), Rashan Paudel (21772689) (author)
Veröffentlicht:	2025
Schlagworte:	Medicine Microbiology Genetics Evolutionary Biology Immunology Infectious Diseases Virology Biological Sciences not elsewhere classified suggested direct capture stimulation assay showed natural cytokine signaling macrophage cell line length cdna sequencing confirmed using lc cell culture compared intron gene structure tertiary levels based sequenced iltv genomes infectious laryngotracheitis virus enhance virus replication conserved gene structure div >< p 4 knockout compared viral genome predicted 8 ), il iltv genome expressing recombinant chicken il expressed viral il viral il 4 gene viral mimics precisely conserved highly expressed comparable levels 5 ), vertebrate il functional il vivo </ vivo ,</ vitro </ vertebrate interleukin vertebrate homologs subsequently identified results represent protein expression phylogenetic analyses persisting within perpetuating strategies parental strain mature transcript infected cells immune response galliformes </ functional interleukin first report computational modeling cellular receptors 4 homologs
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Comparison of vIL-4, cIL-4 and cIL-13 amino acid similarity and predicted receptor interactions.

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