Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation

<p dir="ltr">NADPH oxidase 4 (NOX4) regulates endothelial inflammation by producing hydrogen peroxide (H2O2) and to a lesser extent O2•-. The ratio of NOX4-derived H2O2 and O2•- can be altered by coenzyme Q (CoQ) mimics. Therefore, we hypothesize that cytochrome b5 reductase 3 (CYB5R...

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المؤلف الرئيسي:	Shuai Yuan (17775132) (author)
مؤلفون آخرون:	Scott A. Hahn (21438663) (author), Megan P. Miller (21438655) (author), Michael J. Calderon (9707785) (author), Mara Sullivan (21438631) (author), Atinuke M. Dosunmu-Ogunbi (494832) (author), Marco Fazzari (509175) (author), Yao Li (154923) (author), Michael Reynolds (1691707) (author), Katherine C. Wood (8103491) (author), Claudette M. St Croix (15083481) (author), Donna Stolz (267760) (author), Eugenia Cifuentes-Pagano (2657626) (author), Placido Navas (21438653) (author), Sruti Shiva (5065025) (author), Francisco J. Schopfer (1863409) (author), Patrick J. Pagano (2657635) (author), Adam C. Straub (11681074) (author)
منشور في:	2025
الموضوعات:	Enzymes Signal transduction Cardiology (incl. cardiovascular diseases) CYB5R3 NOX4 Coenzyme Q ROS Inflammation
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Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation

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