Image 1_JAK/STAT in human diseases: a common axis in immunodeficiencies and hematological disorders.jpeg

Image 1_JAK/STAT in human diseases: a common axis in immunodeficiencies and hematological disorders.jpeg

<p>The JAK-STAT signaling pathway (Janus Kinase-Signal Transducer and Activator of Transcription) is a crucial molecular cascade that regulates immune responses, cell proliferation, and hematopoiesis. Germline or somatic mutations affecting this pathway leads to a wide range of pathologies, fr...

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Bibliographic Details
Main Author: Reda Djidjik (11019228) (author)
Other Authors: Lydia Lamara Mahammed (11019210) (author), Lilya Meriem Berkani (22186369) (author), Ines Allam (12440343) (author), Alaa Hamidou Benmoussa (22801934) (author), Merzak Gharnaout (5714753) (author), Brahim Belaid (11019207) (author)
Published: 2025
Subjects:
Genetic Immunology
cancers
inborn errors of immunity
JAK
mutations
signaling pathway
STAT
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