Characterization of meiotic prophase progression and crossover formation.

Characterization of meiotic prophase progression and crossover formation.

<p><b>A.</b> Prophase I control and <i>Sas4</i> cKO spermatocytes from 14 and 20 dpp mice were immunolabeled against γ-H2AX (cyan), SYCP3 (red and grey outset below corresponding image), and stained with DAPI (grey outset below corresponding image). Scale bars = 10 µm....

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Bibliographic Details
Main Author: Marnie W. Skinner (14660004) (author)
Other Authors: Paula B. Nhan (18471984) (author), Carter J. Simington (17145830) (author), Philip W. Jordan (14660022) (author)
Published: 2025
Subjects:
Biophysics
Biochemistry
Cell Biology
Genetics
Molecular Biology
Developmental Biology
Cancer
Physical Sciences not elsewhere classified
understanding certain conditions
pericentriolar matrix proteins
murine conditional knockout
disrupted acrosome morphology
constricted perinuclear rings
male infertility associated
div >< p
round spermatid formation
require centriole duplication
mice </ p
male germ cells
centriole duplication
male fertility
sas4 </
centriole biogenesis
traditionally viewed
still capable
sperm maturation
organizing centers
meiotic divisions
inherited fewer
infertile due
functional spermatozoa
form flagella
findings demonstrate
critical component
chromosome segregation
centrosomal mtoc
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