Figure 3 from Bcl-xL Is a Key Mediator of Apoptosis Following KRAS<sup>G12C</sup> Inhibition in <i>KRAS<sup>G12C</sup></i>-mutant Colorectal Cancer

Figure 3 from Bcl-xL Is a Key Mediator of Apoptosis Following KRAS<sup>G12C</sup> Inhibition in <i>KRAS<sup>G12C</sup></i>-mutant Colorectal Cancer

<p>Bcl-xL regulates intrinsic resistance to KRAS<sup>G12C</sup> inhibition in <i>KRAS</i><sup>G12C</sup> MT colorectal cancer<b>. A,</b> Targeted siRNA screen in SW837 and SNU1411 cells. Top: SW837 and SNU1411 cells were reverse transfected with...

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Detalles Bibliográficos
Autor Principal:	Hajrah Khawaja (15090810) (author)
Outros autores:	Rebecca Briggs (15090813) (author), Cheryl H. Latimer (15090816) (author), Mustasin Rassel (15090819) (author), Daryl Griffin (15090822) (author), Lyndsey Hanson (15090825) (author), Alberto Bardelli (15046646) (author), Frederica Di Nicolantonio (15090828) (author), Simon S. McDade (14939679) (author), Christopher J. Scott (15090831) (author), Shauna Lambe (15090834) (author), Manisha Maurya (15090837) (author), Andreas U. Lindner (15033719) (author), Jochen H.M. Prehn (15033731) (author), Jose Sousa (15090840) (author), Chris Winnington (15090843) (author), Melissa J. LaBonte (15090846) (author), Sarah Ross (15090849) (author), Sandra Van Schaeybroeck (15090852) (author)
Publicado:	2025
Subjects:	Cancer Cancer Biology Therapeutic Research and Development Drug Resistance Novel mechanisms Gastrointestinal Cancers Colorectal cancer Oncogenes & Tumor Suppressors Kras
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