Image1_An ultra-sensitive suboptimal protospacer adjacent motif enhanced rolling circle amplification assay based on CRISPR/Cas12a for detection of miR-183.TIF

Image1_An ultra-sensitive suboptimal protospacer adjacent motif enhanced rolling circle amplification assay based on CRISPR/Cas12a for detection of miR-183.TIF

Introduction<p>MicroRNAs (miRNAs) have been recognized as promising diagnostic biomarkers for Diabetic Retinopathy (DR) due to their notable upregulation in individuals with the condition. However, the development of highly sensitive miRNAs assays for the rapid diagnosis of DR in clinical sett...

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Main Author: Zhiquan Lu (9945004) (author)
Other Authors: Shijing Wang (9983114) (author), Ping Li (31981) (author), Huasheng Yang (4002230) (author), Sanyang Han (1595143) (author), Shaochong Zhang (130298) (author), Lan Ma (112478) (author)
Published: 2024
Subjects:
Biotechnology
Biological Engineering
Genetic Engineering
Biomarkers
Biomaterials
Biomechanical Engineering
Biomedical Engineering not elsewhere classified
Synthetic Biology
Agricultural Marine Biotechnology
Bioremediation
Bioprocessing, Bioproduction and Bioproducts
Industrial Biotechnology Diagnostics (incl. Biosensors)
Industrial Microbiology (incl. Biofeedstocks)
Industrial Molecular Engineering of Nucleic Acids and Proteins
Industrial Biotechnology not elsewhere classified
Medical Biotechnology Diagnostics (incl. Biosensors)
Medical Molecular Engineering of Nucleic Acids and Proteins
Regenerative Medicine (incl. Stem Cells and Tissue Engineering)
Medical Biotechnology not elsewhere classified
diabetic retinopathy
CRISPR/Cas12a
microRNA
rolling circle amplification
fluorescence
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