The frequencies of cytotoxic mediators production of CD56dimCD16+NKG2A+NKG2C-CD57- NK cells in HFRS patients with different disease severity or at different stages.

Representative flow cytometric plots and the comparison of the expression of perforin (A and B), granzyme B (C and D) and CD107a (E and F) on CD56dimCD16+NKG2A+NKG2C-CD57- NK cells among mild/moderate HFRS patients, severe/critical HFRS patients and uninfected controls, respectively. Repres...

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Bibliographic Details
Main Author:	Manling Xue (14262008) (author)
Other Authors:	Kang Tang (722079) (author), Yusi Zhang (383393) (author), Xiaoyue Xu (712736) (author), Chunmei Zhang (67508) (author), Jiajia Zuo (10258540) (author), Fenglan Wang (11652412) (author), Xiyue Zhang (4288279) (author), Xuyang Zheng (3755152) (author), Ran Zhuang (383394) (author), Yun Zhang (131894) (author), Boquan Jin (383395) (author), Ying Ma (123771) (author)
Published:	2025
Subjects:	Biochemistry Medicine Molecular Biology Immunology Cancer Infectious Diseases Virology Biological Sciences not elsewhere classified infection remain unclear ex vivo </ div >< p detected using ligand cell rna sequencing antiviral immune response dim </ sup enhanced cytolytic capacity peptide affinity detection sup >-</ sup sup >+</ sup derived peptides presented α ), interferon virus infectious diseases receptor binding assay inhibitory receptor cd94 derived peptide complex nk cells showed derived peptides binding capacity nk cells cytotoxicity assay e cells tetramer staining taken together showing activation renal syndrome proliferation phenotypes pathogenesis process hemorrhagic fever hantaan virus functional evaluation flow cytometry findings demonstrate cytotoxic mediators
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The frequencies of cytotoxic mediators production of CD56<sup>dim</sup>CD16<sup>+</sup>NKG2A<sup>+</sup>NKG2C<sup>-</sup>CD57<sup>-</sup> NK cells in HFRS patients with different disease severity or at different stages.

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