Out-of-sample fit and posterior predictive plots for the left inferior temporal region.

Out-of-sample fit and posterior predictive plots for the left inferior temporal region.

<p>The local FKPP model was iteratively calibrated to a ADNI cohort with 41 in-sample subjects and 16 test subjects. Three iterations were run where for each iteration an additional scan from the test subjects were included, starting with a single scan. Posterior predictive trajectories for le...

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Bibliographic Details
Main Author: Pavanjit Chaggar (9515394) (author)
Other Authors: Jacob W. Vogel (17601848) (author), Alexa Pichet Binette (17282919) (author), Travis B. Thompson (9515391) (author), Olof Strandberg (5612342) (author), Niklas Mattsson-Carlgren (15238039) (author), Linda Karlsson (368463) (author), Erik Stomrud (371678) (author), Saad Jbabdi (117812) (author), Stefano Magon (513040) (author), Gregory Klein (4673425) (author), Oskar Hansson (233854) (author), Alain Goriely (1669849) (author)
Published: 2025
Subjects:
Genetics
Molecular Biology
Neuroscience
Biotechnology
Science Policy
Mental Health
Infectious Diseases
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
xlink "> aggregation
two independent cohorts
predict accurately subject
new clinical tool
alzheimer &# 8217
tau pet data
pathological tau seeds
hyperphosphorylated tau protein
rich spatiotemporal pattern
local tau production
disease exhibiting transport
pathologic tau
spatiotemporal process
local production
transport dynamics
sequentially progressing
regional level
potentially providing
early stage
disease timeline
central driver
brain regions
accumulation exhibits
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